The INRatio testing system, used to monitor the clotting time of blood for patients taking oral anticoagulants, is based on HemoSense’s proprietary electrochemical detection technology that combines traditional electrochemistry with modern sensor technologies. This advanced technology eliminates the need for the complex and costly optical detection systems found in other devices; however, the technology is sensitive to the volume of blood delivered to the reaction cell.
The microfluidic test strip for the blood coagulation meter features a die-cut, “candelabra-shaped,” three-channel capillary flow path in the adhesive tape layer for these reaction cells. Because of this critical component’s design, HemoSense recognized that it was essential to find an adhesives supplier that could accurately control the thickness of this material while meeting all of the other functional requirements of the device.
“Adhesives Research was willing to make the investment in time and effort to partner with HemoSense to develop the specification and processes needed to produce the adhesive layer used in the INRatio test strip, which enabled the successful development of this new technology,” said Gary Hewett, executive vice president of Operations for HemoSense.
Adhesives Research was able to meet HemoSense’s needs by providing ARcare® 7841 for use as a spacer tape in the construction of the test strips. 7841 is a 1-mil clear polyester film coated on both sides with Adhesives Research’s AS-110 acrylic, medical-grade pressure-sensitive adhesive. It features excellent conformability and good bonding properties, and is compatible with biological fluids and reagents. The thin, flexible properties of this film allowed for the clean die cutting required by HemoSense’s unique design. Overall, ARcare spacer tapes offer tight tolerance and uniform total product thickness. This reliability of product dimensions produces consistent fluid volumes and spaces that allow for more concise measurement of fluids in the channel, an effective means of reducing measurement error in diagnostic devices.
For more information about HemoSense, visit www.HemoSense.com.