The TAH closed-end cartridge system offers superior quality at a significant cost savings. The robust uni-body design has a rugged connection between cylinders, preventing breakage and misalignment, and offers a generous lead-in for ease of piston insertion. The cartridge system also features multi-seal pistons with pre-staged bleed plugs and a wide shelf at the back end of the cartridge for a foil seal option. The re-sealable cap offers identification marks to prevent cross-contamination, and the hermetically sealed outlet breaks off cleanly, providing longer shelf life for cartridge contents. The cartridge system is available in 50, 200, 400 and 600 ml sizes.