METTLER TOLEDO: Online Resources
This company has announced the availability of new web-based resources focused on heat transfer and scaleup and mass transfer to control the reaction rate. Addressing common challenges for chemists and engineers working in process development in the pharmaceutical and fine chemical industries, the online resources reportedly provide information to scaleup new products faster with decreased costs and high quality.
A precise heat transfer coefficient is required to successfully scaleup a chemical process from lab to plant. Measuring the reactor and jacket temperature can enable scientists to calculate the thermal resistance. Thermal resistance is used to model the heat transfer and determine the necessary predictions for reactors at large scale. Reaction calorimetry is required to define parameters that influence heat transfer and the heat transfer coefficients to develop models to maximize manufacturing productivity.
Mixing is the removal or decrease of inhomogeneity between phases that are either miscible or immiscible. Process scaleup and optimization necessitates quantifying the impact of mixing on the reaction rate. Precise experiments can be run automatically in a lab reactor system to investigate the mass transfer correlation, and reportedly allow for the quick adjustment of the gas/liquid mass transfer and reaction rate. This accomplishes the required conditions for process scaleup or scale-down.
For more information, visit www.mt.com.