In a critical advancement for U.S. production of 100% bio-based ingredients, Locus Fermentation Solutions (Locus FS), a domestic bio-manufacturing leader, announced expansion of Toxic Substance Control Act (TSCA) registration for its biosurfactants from the Environmental Protection Agency (EPA). The company reports that this approval makes Locus FS the first and only domestic biosurfactant supplier that can produce commercial volumes within the United States, using a diverse range of renewable raw materials. It is a crucial milestone for broadening use of the sustainable ingredients across key applications in agriculture, oil and gas, mining, home care, personal care, industrial, and others.

Urgent Need

The chemical industry is experiencing a rapid and significant shift towards increased adoption of bio-based ingredients. Fermentation-produced biosurfactants have emerged as a top alternative to chemical ingredients due to their unmatched environmental and performance benefits. The versatile and 100% bio-based ingredients can be used in applications across a wide range of consumer and industrial markets.

Because of this, recent legislation has highlighted the urgent need to increase domestic production of these biosurfactant ingredients. However, producing biosurfactants at scale within the United States requires EPA TSCA registration through a Premanufacture Notice (PMN) approval process.

Dr. Maxwell Shumba, VP of Global Regulatory Affairs & Strategy for Locus FS, commented, “Expanding the list of TSCA-approved biosurfactants significantly broadens the availability of sustainable chemical alternatives that prioritize environmental safety and regulatory compliance. Demand from formulators seeking high-performance, eco-friendly biosurfactants has been and continues to be high. The TSCA expansion reaffirms our position as a leading biosurfactant supplier to meet those needs. Our diligent work done over multiple years is revolutionizing the chemical industry while also paving the way for other biosurfactant companies.”

Commercial Volumes

Currently, Locus FS reports that it stands as the only U.S. biosurfactant producer with PMN, enabling production of the ingredients at commercial volumes. The approval includes both linear and lactonic, and hydrolyzed and non-hydrolyzed versions of the company’s glycolipids for use in consumer and industrial applications.

“Other biomanufacturing companies are limited to importing biosurfactants at a significant cost and cannot produce them within the US. Locus FS’ TSCA approval allows us to domestically manufacture an impressive annual volume far larger than what’s typical,” Shumba said. “This regulatory expansion grants Locus FS a significant advantage.”

Locus FS also has REACH registrations from the European Chemicals Agency (ECHA) and the UK, enabling distribution of the biosurfactants across the EU and Great Britain through its ingredients division.

Sustainable Ingredient Choice

Locus FS’ biosurfactants offer a solution to regulatory challenges and concerns related to 1,4-Dioxane, Proposition 65 labeling and palm oil production that can be common with other bio-based and chemical ingredients. The biosurfactants are derived from responsibly sourced, 100% renewable resources such as fatty acids and carbohydrates. They are free of palm oil, 1,4-dioxane, formaldehyde, ethylene oxide (EO) or other Proposition 65 regulated trace chemicals. This sustainable approach ensures minimal environmental impact with a low carbon footprint and premium performance.

In addition to being USDA Certified 100% Biobased, readily biodegradable and non-GMO, the biosurfactants are extremely versatile and multifunctional. They have proven success in applications across key global industries such as agriculture, animal nutrition, consumer products, health and wellness, industrial products, mining, and oil and gas.

Locus Fermentation Solutions (Locus FS) uses patented biomanufacturing technology to deliver biological alternatives to chemicals that accelerate the profitable meeting of decarbonization goals for clients. For more information on Locus Fermentation Solutions’ TSCA-certified biosurfactants and their application in various industrial and CPG formulations, please visit LocusFS.com.